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Resistant Mycoplasma Pneumonia

Case Report, Volume 18 Issue 2 – April to June 2025

Lima Ann Mathewa, T U Sukumaranb

a. DNB Resident, Caritas Matha Hospital, Kottayam; b. Professor and Senior Consultant, Caritas Matha Hospital, Kottayam*

ABSTRACT

Mycoplasma pneumoniae is recognized as a leading cause of community-acquired lower respiratory tract infection in children, which accounts for about 25-30% of pneumonia in children. Macrolides are the first-line treatment for M. pneumoniae infections. However, the extensive use of macrolides in clinical practice has resulted in the emergence of macrolide-resistant M. pneumoniae (MRMP), which has a negative impact on treatment outcomes.1

Here we present a case of severe, Macrolide-resistant Mycoplasma pneumoniae infection in a previously healthy 9-year-old male, culminating in necrotizing pneumonia,  complicated by bilateral pleural effusion. The case highlights the challenges in diagnosing and managing atypical pneumonia unresponsive to first-line therapies.

 

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