Authors

Prof. Dr BabuRaj P, MD^a, Dr Dyna T Denny, MBBS^a, Dr Harikrishnan B L, MD^b
a Department of General Medicine, Jubilee Mission Medical College & Research Institute, Thrissur;
^b Department of Emergency Medicine, Jubilee Mission Medical College & Research Institute, Thrissur

Abstract

Rosai Dorfman Disease is a rare benign lymphoproliferative disease which is an unusual cause for lymphadenopathy. We report a case of 16 year old male who presented with massive bilateral cervical lymphadenopathy of 11/2 months duration. Blood investigations were normal except for raised ESR. Excision biopsy was done. Histological examination revealed mixed cellularity consisting of lymphocytes, plasma cells, numerous histiocytes exhibiting marked emperipolesis; suggestive of Rosai-Dorfman Disease (Sinus histiocytosis with massive lymphadenopathy). He was started on low dose steroids. The patient is being followed up; the case is being reported for its rarity.

Full Article

Download Full Article (PDF)