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Occurrence of Acute Myeloid Leukaemia in a Patient with Cutaneous Sarcoidosis

Case Report, Volume 10 Issue 3 – July to September 2017

Authors

Manikoth Payyanadan Binitha1, Anza Khader1, Mohamed Shaan2, Ahmed Nadeem3
1Department of Dermatology and Venereology, Government Medical College, Kozhikode, Kerala
2Department of General Medicine, Government Medical College, Manjeri, Kerala, India
3Assistant Surgeon, Kannur, Kerala


Abstract

There is a close relationship between sarcoidosis and malignancy, which is more pronounced in patients with cutaneous sarcoidosis. An intense T helper cell response occurs in sarcoidosis, with an imbalance between the activity of effector and regulatory T cells, which could be responsible for the coexistence of malignancy. We present a patient who developed acute myeloid leukaemia one and a half years after she was diagnosed with cutaneous sarcoidosis.
Keywords: Cutaneous Sarcoidosis, Acute Myeloid Leukaemia


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